![]() The latter group makes up a minority of those who report reflux induced symptoms in population surveys. Schema illustrating the need to distinguish between individuals who report minor reflux induced symptoms and those in whom these symptoms have significant impacts. The small number of studies eligible for inclusion in this review highlights the need for global consensus on a symptom based definition of GORD. The disease is more common in the Western world than in Asia, and the low rate of incidence relative to prevalence reflects its chronicity. A number of potential risk factors (for example, an immediate family history and obesity) and comorbidities (for example, respiratory diseases and chest pain) associated with GORD were identified.ĭata reported in this systematic review can be interpreted with confidence as reflecting the epidemiology of “true” GORD. The incidence in the Western world was approximately person years. ![]() Data on factors associated with GORD were also evaluated.Īn approximate prevalence of 10–20% was identified for GORD, defined by at least weekly heartburn and/or acid regurgitation in the Western world while in Asia this was lower, at less than 5%. The prevalence and incidence of GORD was estimated from 15 studies which defined GORD as at least weekly heartburn and/or acid regurgitation and met criteria concerning sample size, response rate, and recall period. ![]() The small number of studies eligible for inclusion in this review highlights the need for global consensus on a symptom based definition of GORD.Ī systematic review of the epidemiology of gastro-oesophageal reflux disease (GORD) has been performed, applying strict criteria for quality of studies and the disease definition used. Data reported in this systematic review can be interpreted with confidence as reflecting the epidemiology of "true" GORD. A number of potential risk factors (for example, an immediate family history and obesity) and comorbidities (for example, respiratory diseases and chest pain) associated with GORD were identified. An approximate prevalence of 10-20% was identified for GORD, defined by at least weekly heartburn and/or acid regurgitation in the Western world while in Asia this was lower, at less than 5%. Data on factors associated with GORD were also evaluated. A systematic review of the epidemiology of gastro-oesophageal reflux disease (GORD) has been performed, applying strict criteria for quality of studies and the disease definition used.
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